A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.

doi:10.1016/j.jaci.2013.01.057

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Article

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis.

The Journal of allergy and clinical immunology - 1 Aug 2013

Esparza-Gordillo Jorge, Schaarschmidt Heidi, Liang Liming, Cookson William, Bauerfeind Anja, Lee-Kirsch Min-Ae, Nemat Katja, Henderson John, Paternoster Lavinia, Harper John I, Mangold Elisabeth, Nothen Markus M, Rüschendorf Franz, Kerscher Tamara, Marenholz Ingo, Matanovic Anja, Lau Susanne, Keil Thomas, Bauer Carl-Peter, Kurek Michael, Ciechanowicz Andrzej, Macek Milan, Franke Andre, Kabesch Michael, Hubner Norbert, Abecasis Gonçalo, Weidinger Stephan, Moffatt Miriam, Lee Young-Ae

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin disease. Previous studies have revealed shared genetic determinants among different inflammatory disorders, suggesting that markers associated with immune-related traits might also play a role in AD. OBJECTIVE: We sought to identify novel genetic risk factors for AD. METHODS: We examined the results of all genome-wide association studies from a...

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Identifiers

PMID: 23582566
DOI: 10.1016/j.jaci.2013.01.057

Genes

ERBB3
RAD50
RUNX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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