Article
Single nucleotide variations in genes associated with innate immunity are enriched in Japanese adult cases of face and neck type atopic dermatitis.
Journal of dermatological science - 1 Feb 2021
Yasuda-Sekiguchi Fumiyo, Shiohama Aiko, Fukushima Ayano, Obata Shoko, Mochimaru Naoko, Honda Aki, Kawasaki Hiroshi, Kubo Akiharu, Ebihara Tamotsu, Amagai Masayuki, Sasaki Takashi
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is heterogenous in terms of phenotype as well as genetic and environmental factors, while its associated genetic factors and pathophysiology are not fully understood. OBJECTIVE: We identify novel genetic factors enriched in a subgroup of AD patients with characteristic clinical features. METHODS: We clinically subgrouped 18 AD patients who exhibited distinctive characteristic of...
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