Article
Rapid high-resolution HLA genotyping by MinION Oxford nanopore sequencing for deceased donor organ allocation.
HLA - 1 Aug 2020
De Santis Dianne, Truong Linh, Martinez Patricia, D'Orsogna Lloyd
Abstract excerpt
Recently, HLA epitopes on donor HLA molecules have been shown to be important in the success of solid organ transplantation. However, these epitopes can only be defined using high-resolution typing results of which are often not available prior to deceased donor allocation. The ability to perform high-resolution typing at all HLA loci for deceased organ donor allocation prior to transplantation would have major...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
