Article
Utilizing nanopore sequencing technology for the rapid and comprehensive characterization of eleven HLA loci; addressing the need for deceased donor expedited HLA typing.
Human immunology - 1 Aug 2020
Mosbruger Timothy L, Dinou Amalia, Duke Jamie L, Ferriola Deborah, Mehler Hilary, Pagkrati Ioanna, Damianos Georgios, Mbunwe Eric, Sarmady Mahdi, Lyratzakis Ioannis, Tishkoff Sarah A, Dinh Anh, Monos Dimitri S
Abstract excerpt
The comprehensive characterization of human leukocyte antigen (HLA) genomic sequences remains a challenging problem. Despite the significant advantages of next-generation sequencing (NGS) in the field of Immunogenetics, there has yet to be a single solution for unambiguous, accurate, simple, cost-effective, and timely genotyping necessary for all clinical applications. This report demonstrates the benefits of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.