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Article

Cost-efficient high-throughput HLA typing by MiSeq amplicon sequencing.

BMC genomics - 24 Jan 2014

Lange Vinzenz, Böhme Irina, Hofmann Jan, Lang Kathrin, Sauter Jürgen, Schöne Bianca, Paul Patrick, Albrecht Viviane, Andreas Johanna M, Baier Daniel M, Nething Jochen, Ehninger Ulf, Schwarzelt Carmen, Pingel Julia, Ehninger Gerhard, Schmidt Alexander H

Abstract excerpt

BACKGROUND: A close match of the HLA alleles between donor and recipient is an important prerequisite for successful unrelated hematopoietic stem cell transplantation. To increase the chances of finding an unrelated donor, registries recruit many hundred thousands of volunteers each year. Many registries with limited resources have had to find a trade-off between cost and resolution and extent of typing for newly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 24460756
DOI: 10.1186/1471-2164-15-63
PMCID: PMC3909933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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