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Characterization of macrophage phenotype, redox, and purinergic response upon chronic treatment with methionine and methionine sulfoxide in mice.

Amino acids - 1 Apr 2020

Franceschi Thaís S, Soares Mayara S P, Pedra Nathalia S, Bona Natália P, Spohr Luiza, Teixeira Fernanda C, do Couto Carlus A T, Spanevello Roselia M, Deon Marion, Vargas Carmen R, Braganhol Elizandra, Stefanello Francieli M

Abstract excerpt

Hypermethioninemia is a disorder characterized by high plasma levels of methionine (Met) and its metabolites such as methionine sulfoxide (MetO). Studies have reported associated inflammatory complications, but the mechanisms involved in the pathophysiology of hypermethioninemia are still uncertain. The present study aims to evaluate the effect of chronic administration of Met and/or MetO on phenotypic...

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PMID: 32246211
DOI: 10.1007/s00726-020-02841-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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