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Article

Carbon monoxide-releasing molecule, CORM-3, modulates alveolar macrophage M1/M2 phenotype in vitro.

Inflammopharmacology - 1 Apr 2018

Yamamoto-Oka Hiroko, Mizuguchi Shinjiro, Toda Michihito, Minamiyama Yukiko, Takemura Shigekazu, Shibata Toshihiko, Cepinskas Gediminas, Nishiyama Noritoshi

Abstract excerpt

Alveolar macrophages are key contributors to both the promotion and resolution of inflammation in the lung and are categorized into pro-inflammatory (M1) and anti-inflammatory (M2) phenotypes. The change in M1/M2 balance has been reported in various pulmonary diseases and is a target for therapeutic intervention. The aim of this study was to assess the modulation of M1/M2 phenotype in alveolar macrophages by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28674739
DOI: 10.1007/s10787-017-0371-y

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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