Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The phenotype of peritoneal mouse macrophages depends on the mitochondria and ATP/ADP homeostasis.

Cellular immunology - 1 Feb 2018

Chen Wei, Sandoval Hector, Kubiak Jacek Z, Li Xian C, Ghobrial Rafik M, Kloc Malgorzata

Abstract excerpt

Different macrophage subtypes have different morphologies/shapes and functions. Naïve M0 macrophages are elongated. Pro-inflammatory M1 that produce the bactericidal molecule iNos are round. Anti-inflammatory M2 macrophages that produce the pro-healing enzyme Arg-1 are highly elongated. We showed previously that the morphologies of M0 and M2 but not M1 macrophages are RhoA-dependent. Macrophage-specific deletion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Diphosphate
Share to Adenosine Triphosphate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeostasis

Share to Macrophages

Share to Macrophages, Peritoneal

Share to Mitochondria

Share to Peritoneal Cavity

Source

Identifiers

PMID: 29129293
DOI: 10.1016/j.cellimm.2017.11.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The phenotype of peritoneal mouse macrophages depends on the mitochondria and ATP/ADP homeostasis.PMID 29129293Read ↗

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.Semantic proximity Read ↗

Pro-inflammatory macrophage activation does not require inhibition of mitochondrial respirationSemantic proximity Read ↗

Dissonant response of M0/M2 and M1 bone-marrow-derived macrophages to RhoA pathway interference.Semantic proximity Read ↗

Macrophage activation as an archetype of mitochondrial repurposing.Semantic proximity Read ↗

A20 restriction of nitric oxide production restores macrophage bioenergetic balanceSemantic proximity Read ↗

How Mitochondrial Metabolism Contributes to Macrophage Phenotype and Functions.Semantic proximity Read ↗

Fish Macrophages Show Distinct Metabolic Signatures Upon Polarization.Semantic proximity Read ↗

Dissecting Metabolic Landscape of Alveolar MacrophageSemantic proximity Read ↗

The Role of Metabolic Remodeling in Macrophage Polarization and Its Effect on Skeletal Muscle Regeneration.Semantic proximity Read ↗

Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolismSemantic proximity Read ↗

CPT1A-IL-10-mediated macrophage metabolic and phenotypic alterations ameliorate acute lung injury.Semantic proximity Read ↗

Mitochondrial metabolism mediated macrophage polarization in chronic lung diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.