Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels.

PLoS neglected tropical diseases - 1 Apr 2020

Weinschutz Mendes Hellen, Boldt Angelica Beate Winter, von Rosen Seeling Stahlke Ewalda, Jensenius Jens Christian, Thiel Steffen, Messias-Reason Iara J Taborda

Abstract excerpt

BACKGROUND: Deposition of complement factors on Mycobacterium leprae may enhance phagocytosis. Such deposition may occur through the lectin pathway of complement. Three proteins of the lectin pathway are produced from the gene MASP1: Mannan-binding lectin-associated serine protease 1 (MASP-1) and MASP-3 and mannan-binding lectin-associated protein of 44 kDa (MAp44). Despite their obvious importance, the roles...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cross-Sectional Studies

Share to Haplotypes

Share to Leprosy

Share to Mannose-Binding Protein-Associated Serine Proteases

Share to Mycobacterium leprae

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 32240160
DOI: 10.1371/journal.pntd.0007534
PMCID: PMC7162614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels.PMID 32240160Read ↗

Adding <i>MASP1</i> to the lectin pathway – leprosy association puzzle: hints from gene polymorphisms and protein levelsSemantic proximity Read ↗

Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors.Semantic proximity Read ↗

Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy.Semantic proximity Read ↗

Leprosy association with low MASP-2 levels generated by MASP2 haplotypes and polymorphisms flanking MAp19 exon 5.Semantic proximity Read ↗

Association of MBL2 Exon 1 Polymorphisms With Multibacillary Leprosy.Semantic proximity Read ↗

Association of a new FCN3 haplotype with high ficolin-3 levels in leprosy.Semantic proximity Read ↗

Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity.Semantic proximity Read ↗

The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm.Semantic proximity Read ↗

Susceptibility to leprosy is associated with M-ficolin polymorphisms.Semantic proximity Read ↗

Mannose-binding lectin: structure, function, genetics and disease associations.Semantic proximity Read ↗

Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes.Semantic proximity Read ↗

Genetic variants, structural, and functional changes of Myelin Protein Zero and Mannose-Binding Lectin 2 protein involved in immune response and its allelic transmission in families of patients with leprosy in Colombia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.