Genetic variants, structural, and functional changes of Myelin Protein Zero and Mannose-Binding Lectin 2 protein involved in immune response and its allelic transmission in families of patients with leprosy in Colombia.

doi:10.1016/j.meegid.2018.04.002

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genetic variants, structural, and functional changes of Myelin Protein Zero and Mannose-Binding Lectin 2 protein involved in immune response and its allelic transmission in families of patients with leprosy in Colombia.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2018

Cardona-Pemberthy Viviana, Rendón Michelle, Beltrán Juan Camilo, Soto-Ospina Alejandro, Muñoz-Gomez Amalia, Araque-Marín Pedronel, Corredor Mauricio, Bedoya Gabriel, Cardona-Castro Nora

Abstract excerpt

Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Genetic factors associated with immune response contribute to infection development and disease. M. leprae has the capacity to invade Schwann cells in the peripheral nervous system and cause neuropathy. However, while the responsible molecular mechanisms remain to be fully unveiled, they have begun being elucidated. We studied genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colombia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to MBL2 gene

Share to MPZ gene

Share to Leprosy

Share to Mannose-Binding Lectin

Share to Models, Molecular

Share to Myelin P0 Protein

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 29627640
DOI: 10.1016/j.meegid.2018.04.002

Genes

MPZ
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants, structural, and functional changes of Myelin Protein Zero and Mannose-Binding Lectin 2 protein involved in immune response and its allelic transmission in families of patients with leprosy in Colombia.PMID 29627640Read ↗

Association of MBL2 Exon 1 Polymorphisms With Multibacillary Leprosy.Semantic proximity Read ↗

The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm.Semantic proximity Read ↗

Low-MBL producing genotypes playing a role on protection to leprosy and its multibacillary forms in a highly endemic area for leprosy in BrazilSemantic proximity Read ↗

Adding <i>MASP1</i> to the lectin pathway – leprosy association puzzle: hints from gene polymorphisms and protein levelsSemantic proximity Read ↗

Adding MASP1 to the lectin pathway-Leprosy association puzzle: Hints from gene polymorphisms and protein levels.Semantic proximity Read ↗

Leprosy association with low MASP-2 levels generated by MASP2 haplotypes and polymorphisms flanking MAp19 exon 5.Semantic proximity Read ↗

Molecular epidemiology of leprosy: An updateSemantic proximity Read ↗

How many single-nucleotide polymorphisms (SNPs) must be tested in order to prove susceptibility to bacterial meningitis in children? Analysis of 11 SNPs in seven genes involved in the immune response and their effect on the susceptibility to bacterial meningitis in children.Semantic proximity Read ↗

MBL2 gene variants and susceptibility to meningitis in Egyptian patients.Semantic proximity Read ↗

Role of toll-interacting protein gene polymorphisms in leprosy Mexican patients.Semantic proximity Read ↗

Genetics of leprosy: today and beyond.Semantic proximity Read ↗

Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.