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Article

Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI.

Nucleic acids research - 21 May 2020

Miyazono Ken-Ichi, Wang Delong, Ito Tomoko, Tanokura Masaru

Abstract excerpt

R.PabI is a restriction DNA glycosylase that recognizes the sequence 5'-GTAC-3' and hydrolyses the N-glycosidic bond of adenine in the recognition sequence. R.PabI drastically bends and unwinds the recognition sequence of double-stranded DNA (dsDNA) and flips the adenine and guanine bases in the recognition sequence into the catalytic and recognition sites on the protein surface. In this study, we determined the...

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Identifiers

PMID: 32232412
DOI: 10.1093/nar/gkaa184
PMCID: PMC7229829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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