Article
DNA recognition by DNase I.
Journal of molecular recognition : JMR - 1 Jun 1994
Suck D
Abstract excerpt
Bovine pancreatic DNase I shows a strong preference for double-stranded substrates and cleaves DNA with strongly varying cutting rates suggesting that the enzyme recognises sequence-dependent structural variations of the DNA double helix. The complicated cleavage pattern indicates that several lo...
Topics
- Animals
- Base Sequence
- Binding Sites
- Cattle
- DNA
- Deoxyribonuclease I
- In Vitro Techniques
- Kinetics
- Models, Molecular
- Molecular Sequence Data
- Molecular Structure
- Mutation
- Nucleic Acid Conformation
- Protein Conformation
- Substrate Specificity