Article
DNA recognition by DNase I.
Journal of molecular recognition : JMR - 1 Jun 1994
Suck D
Abstract excerpt
Bovine pancreatic DNase I shows a strong preference for double-stranded substrates and cleaves DNA with strongly varying cutting rates suggesting that the enzyme recognises sequence-dependent structural variations of the DNA double helix. The complicated cleavage pattern indicates that several local as well as global helix parameters influence the cutting frequency of DNase I at a given bond. The high resolution...
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