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Article

Activity and specificity of the bacterial PD-(D/E)XK homing endonuclease I-Ssp6803I.

Journal of molecular biology - 6 Feb 2009

Zhao Lei, Pellenz Stefan, Stoddard Barry L

Abstract excerpt

The restriction endonuclease fold [a three-layer alpha-beta sandwich containing variations of the PD-(D/E)XK nuclease motif] has been greatly diversified during evolution, facilitating its use for many biological functions. Here we characterize DNA binding and cleavage by the PD-(D/E)XK homing endonuclease I-Ssp6803I. Unlike most restriction endonucleases harboring the same core fold, the specificity profile of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19038269
DOI: 10.1016/j.jmb.2008.10.096
PMCID: PMC3008403

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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