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Article

Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria.

Scientific reports - 6 Apr 2017

Zhou Yingqin, Luo Hao, Liu Zhongchuan, Yang Mu, Pang Xiaoyun, Sun Fei, Wang Ganggang

Abstract excerpt

Bacterial primase initiates the repeated synthesis of short RNA primers that are extended by DNA polymerase to synthesize Okazaki fragments on the lagging strand at replication forks. It remains unclear how the enzyme recognizes specific initiation sites. In this study, the DnaG primase from Bacillus subtilis (BsuDnaG) was characterized and the crystal structure of the RNA polymerase domain (RPD) was determined....

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Identifiers

PMID: 28386108
DOI: 10.1038/s41598-017-00767-8
PMCID: PMC5429622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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