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Anchor Away - A Fast, Reliable and Reversible Technique To Inhibit Proteins in Drosophila melanogaster.

G3 (Bethesda, Md.) - 4 May 2020

Bosch Pablo Sanchez, Pepperl Julia, Basler Konrad

Abstract excerpt

Several techniques have been developed to study specific gene function in loss-of-function situations. In Drosophila melanogaster, RNAi and the generation of mutant clones are widely used. However, both techniques have the limitation that there is a significant time lag before gene function is abolished. Given the relatively rapid development of Drosophila, such perdurance is a serious impediment to study gene...

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PMID: 32217630
DOI: 10.1534/g3.120.401055
PMCID: PMC7202031

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