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Article

Targeted protein depletion in Saccharomyces cerevisiae by activation of a bidirectional degron.

BMC systems biology - 29 Dec 2010

Jungbluth Marc, Renicke Christian, Taxis Christof

Abstract excerpt

BACKGROUND: Tools for in vivo manipulation of protein abundance or activity are highly beneficial for life science research. Protein stability can be efficiently controlled by conditional degrons, which induce target protein degradation at restrictive conditions. RESULTS: We used the yeast Saccharomyces cerevisiae for development of a conditional, bidirectional degron to control protein stability, which can be...

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Identifiers

PMID: 21190544
DOI: 10.1186/1752-0509-4-176
PMCID: PMC3024245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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