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Article

N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus.

Experimental cell research - 15 May 2020

Beigl Tobias B, Hellesvik Monica, Saraste Jaakko, Arnesen Thomas, Aksnes Henriette

Abstract excerpt

N-alpha-acetyltransferase 80 (NAA80) was recently demonstrated to acetylate the N-terminus of actin, with NAA80 knockout cells showing actin cytoskeleton-related phenotypes, such as increased formation of membrane protrusions and accelerated migration. Here we report that NAA80 knockout cells additionally display fragmentation of the Golgi apparatus. We further employed rescue assays to demonstrate that this...

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Identifiers

PMID: 32209306
DOI: 10.1016/j.yexcr.2020.111961
PMCID: PMC7308165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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