Article

Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish

2024-03-17

Abstract excerpt

Actin is a key component of the cytoskeleton of eukaryotic cells and is involved in numerous cellular functions. In animal cells, actins are uniquely N-terminally processed by a dedicated enzyme machinery to generate their mature acidic and acetylated forms. The final step of this maturation process involves N-terminal acetylation, a reaction catalyzed by NAA80 in humans. In human cell lines, N-terminal acetylatio...

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Literature Corpus work: 391744e6-a7e7-51aa-ab09-013951c470b8
DOI: 10.1101/2024.03.17.585386

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