Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human NAA30 can rescue yeast mak3∆ mutant growth phenotypes.

Bioscience reports - 26 Mar 2021

Drazic Adrian, Varland Sylvia

Abstract excerpt

N-terminal acetylation is an irreversible protein modification that primarily occurs co-translationally, and is catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). The NatC complex (NAA30-NAA35-NAA38) is a major NAT enzyme, which was first described in yeast and estimated to N-terminally acetylate ∼20% of the proteome. The activity of NatC is crucial for the correct functioning of its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Cell Division
Share to Genetic Complementation Test

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 33600573
DOI: 10.1042/BSR20202828
PMCID: PMC7938456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human NAA30 can rescue yeast mak3∆ mutant growth phenotypes.PMID 33600573Read ↗

Expanded in vivo substrate profile of the yeast N-terminal acetyltransferase NatC.Semantic proximity Read ↗

A Saccharomyces cerevisiae model reveals in vivo functional impairment of the Ogden syndrome N-terminal acetyltransferase NAA10 Ser37Pro mutant.Semantic proximity Read ↗

NatC Nalpha-terminal acetyltransferase of yeast contains three subunits, Mak3p, Mak10p, and Mak31p.Semantic proximity Read ↗

NATs at a glanceSemantic proximity Read ↗

Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels.Semantic proximity Read ↗

Proteomic and Genomic Characterization of a Yeast Model for Ogden SyndromeSemantic proximity Read ↗

The biological functions of Naa10 – from amino-terminal acetylation to human diseaseSemantic proximity Read ↗

NAA10 p.(D10G) and NAA10 p.(L11R) Variants Hamper Formation of the NatA N-Terminal Acetyltransferase Complex.Semantic proximity Read ↗

The biological functions of Naa10 — From amino-terminal acetylation to human diseaseSemantic proximity Read ↗

Big fish, little fish: N-terminal acetyltransferase Naa40p proteoforms caught in the actSemantic proximity Read ↗

A functional link between NAD+ homeostasis and N-terminal protein acetylation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Proteomics analyses reveal the evolutionary conservation and divergence of N-terminal acetyltransferases from yeast and humansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.