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Article

The Ubiquitin Ligase CBLC Maintains the Network Organization of the Golgi Apparatus.

PloS one - 1 Jan 2015

Lee Wan Yin, Goh Germaine, Chia Joanne, Boey Adrian, Gunko Natalia V, Bard Frederic

Abstract excerpt

The Golgi apparatus plays a pivotal role in the sorting and post-translational modifications of secreted and membrane proteins. In mammalian cells, the Golgi is organized in stacks of cisternae linked together to form a network with a ribbon shape. Regulation of Golgi ribbon formation is poorly understood. Here we find in an image-based RNAi screen that depletion of the ubiquitin-ligase CBLC induces Golgi...

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Source

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Identifiers

PMID: 26393512
DOI: 10.1371/journal.pone.0138789
PMCID: PMC4579092

Genes

CBLC
SRC
CBL
CBLB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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