Article
Novel Coronin7 interactions with Cdc42 and N-WASP regulate actin organization and Golgi morphology.
Scientific reports - 4 May 2016
Bhattacharya Kurchi, Swaminathan Karthic, Peche Vivek S, Clemen Christoph S, Knyphausen Philipp, Lammers Michael, Noegel Angelika A, Rastetter Raphael H
Abstract excerpt
The contribution of the actin cytoskeleton to the unique architecture of the Golgi complex is manifold. An important player in this process is Coronin7 (CRN7), a Golgi-resident protein that stabilizes F-actin assembly at the trans-Golgi network (TGN) thereby facilitating anterograde trafficking. Here, we establish that CRN7-mediated association of F-actin with the Golgi apparatus is distinctly modulated via the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
