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Rsph9 is critical for ciliary radial spoke assembly and central pair microtubule stability

1 Nov 2018

Abstract excerpt

BACKGROUND INFORMATION: In the "9+2"-type motile cilia, radial spokes (RSs) protruded from the nine peripheral microtubule doublets surround and interact with the central pair (CP) apparatus to regulate ciliary beat. RSPH9 is the human homologue of the essential protozoan RS head protein Rsp9. Its mutations in human primary ciliary dyskinesia patients, however, cause CP loss in a small portion of airway cilia...

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PMID: 30383886
DOI: 10.1111/boc.201800060

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Rsph9 is critical for ciliary radial spoke assembly and central pair microtubule stabilityPMID 30383886Read ↗

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