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Article

RSPH6A is required for sperm flagellum formation and male fertility in mice.

Journal of cell science - 11 Oct 2018

Abbasi Ferheen, Miyata Haruhiko, Shimada Keisuke, Morohoshi Akane, Nozawa Kaori, Matsumura Takafumi, Xu Zoulan, Pratiwi Putri, Ikawa Masahito

Abstract excerpt

The flagellum is an evolutionarily conserved appendage used for sensing and locomotion. Its backbone is the axoneme and a component of the axoneme is the radial spoke (RS), a protein complex implicated in flagellar motility regulation. Numerous diseases occur if the axoneme is improperly formed, such as primary ciliary dyskinesia (PCD) and infertility. Radial spoke head 6 homolog A (RSPH6A) is an ortholog of...

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Identifiers

PMID: 30185526
DOI: 10.1242/jcs.221648
PMCID: PMC6198453

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RSPH6A is required for sperm flagellum formation and male fertility in mice.PMID 30185526Read ↗

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