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Article

Transcription factor p73 regulates Th1 differentiation.

Nature communications - 19 Mar 2020

Ren Min, Kazemian Majid, Zheng Ming, He JianPing, Li Peng, Oh Jangsuk, Liao Wei, Li Jessica, Rajaseelan Jonathan, Kelsall Brian L, Peltz Gary, Leonard Warren J

Abstract excerpt

Inter-individual differences in T helper (Th) cell responses affect susceptibility to infectious, allergic and autoimmune diseases. To identify factors contributing to these response differences, here we analyze in vitro differentiated Th1 cells from 16 inbred mouse strains. Haplotype-based computational genetic analysis indicates that the p53 family protein, p73, affects Th1 differentiation. In cells...

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Source

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Identifiers

PMID: 32193462
DOI: 10.1038/s41467-020-15172-5
PMCID: PMC7081339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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