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Article

T helper 17 cell heterogeneity and pathogenicity in autoimmune disease.

Trends in immunology - 1 Sept 2011

Ghoreschi Kamran, Laurence Arian, Yang Xiang-Ping, Hirahara Kiyoshi, O'Shea John J

Abstract excerpt

T helper (Th)17 cells have been proposed to represent a new CD4(+) T cell lineage that is important for host defense against fungi and extracellular bacteria, and the development of autoimmune diseases. Precisely how these cells arise has been the subject of some debate, with apparent species-specific differences in mice and humans. Here, we describe evolving views of Th17 specification, highlighting the...

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Identifiers

PMID: 21782512
DOI: 10.1016/j.it.2011.06.007
PMCID: PMC3163735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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