Article
Unifying the p73 knockout phenotypes: TAp73 orchestrates multiciliogenesis.
Genes & development - 1 Jun 2016
Napoli Marco, Flores Elsa R
Abstract excerpt
Multiciliogenesis is essential for the function of different epithelia, and its failure results in brain defects, respiratory diseases, and infertility. In this issue of Genes & Development, Nemajerova and colleagues (pp. 1300-1312) reveal the p53 family member and p73 isoform TAp73 as a transcription factor dictating the differentiation of multiciliated cells. Their findings provide the long-awaited unifying...
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