Article
TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses.
Cell death and differentiation - 1 Feb 2013
Tomasini R, Secq V, Pouyet L, Thakur A K, Wilhelm M, Nigri J, Vasseur S, Berthezene P, Calvo E, Melino G, Mak T W, Iovanna J L
Abstract excerpt
The multiple isoforms of p73, a member of the p53 family, share the ability to modulate p53 activities but also have unique properties, leading to a complex and poorly understood functional network. In vivo, p73 isoforms have been implicated in tumor suppression (TAp73(-/-) mice), DNA damage (ΔNp...
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