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Article

Polygenic Multiple Sclerosis Risk and Population-Based Childhood Brain Imaging.

Annals of neurology - 1 May 2020

de Mol C Louk, Jansen Philip R, Muetzel Ryan L, Knol Maria J, Adams Hieab H, Jaddoe Vincent W, Vernooij Meike W, Hintzen Rogier Q, White Tonya J, Neuteboom Rinze F

Abstract excerpt

OBJECTIVE: Multiple sclerosis (MS) is a neurological disease with a substantial genetic component and immune-mediated neurodegeneration. Patients with MS show structural brain differences relative to individuals without MS, including smaller regional volumes and alterations in white matter (WM) microstructure. Whether genetic risk for MS is associated with brain structure during early neurodevelopment remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32162725
DOI: 10.1002/ana.25717
PMCID: PMC7187244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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