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Article

A genetic basis for multiple sclerosis severity: Red herring or real?

Molecular and cellular probes - 1 Dec 2016

Jokubaitis Vilija G, Butzkueven Helmut

Abstract excerpt

Multiple Sclerosis (MS) is an autoimmune degenerative disease of the central nervous system, characterized by multifocal demyelination and neurodegeneration. The genetic architecture of MS is complex, where genetic risk has been attributed to over 100 polymorphic loci each with small odds ratios. MS is a highly heterogeneous disease with numerous clinical and paraclinical endophenotypes. To-date, no genetic...

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Identifiers

PMID: 27546889
DOI: 10.1016/j.mcp.2016.08.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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