Article
Polygenic susceptibility for multiple sclerosis is associated with working memory in low-performing young adults.
Journal of the neurological sciences - 15 Aug 2024
Petrovska J, Coynel D, Freytag V, de Quervain D J-F, Papassotiropoulos A
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is a complex disease with substantial heritability estimates. Besides typical clinical manifestations such as motor and sensory deficits, MS is characterized by structural and functional brain abnormalities, and by cognitive impairment such as decreased working memory (WM) performance. OBJECTIVES: We investigated the possible link between the polygenic risk for MS and WM...
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