Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy.

doi:10.1002/acn3.52291

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy.

Annals of clinical and translational neurology - 1 Mar 2025

De Meo Ermelinda, Portaccio Emilio, Cortese Rosa, Ruano Luis, Goretti Benedetta, Niccolai Claudia, Patti Francesco, Chisari Clara, Gallo Paolo, Grossi Paola, Ghezzi Angelo, Roscio Marco, Mattioli Flavia, Stampatori Chiara, Simone Marta, Viterbo Rosa Gemma, Bonacchi Raffaello, Rocca Assunta Maria, Leveraro Elisa, Giorgio Antonio, De Stefano Nicola, Filippi Massimo, Inglese Matilde, Amato Maria Pia

Abstract excerpt

OBJECTIVES: We aim to investigate cognitive phenotype distribution and MRI correlates across pediatric-, elderly-, and adult-onset MS patients as a function of disease duration. METHODS: In this cross-sectional study, we enrolled 1262 MS patients and 238 healthy controls, with neurological and cognitive assessments. A subset of 222 MS patients and 92 controls underwent 3T-MRI scan for brain atrophy and lesion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atrophy

Share to Cognitive Dysfunction

Share to Cross-Sectional Studies

Share to Gray Matter

Share to Magnetic Resonance Imaging

Share to Multiple Sclerosis

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 39861952
DOI: 10.1002/acn3.52291
PMCID: PMC11920747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pediatric, adult, and late onset multiple sclerosis: Cognitive phenotypes and gray matter atrophy.PMID 39861952Read ↗

Identifying the Distinct Cognitive Phenotypes in Multiple Sclerosis.Semantic proximity Read ↗

Predominant cognitive phenotypes in multiple sclerosis: Insights from patient-centered outcomes.Semantic proximity Read ↗

Identifying neuropsychological phenotypes in multiple sclerosis using latent profile analysis.Semantic proximity Read ↗

A taxonomy of cognitive phenotypes in Multiple Sclerosis: a 1-year longitudinal study.Semantic proximity Read ↗

A proposed new taxonomy of cognitive phenotypes in multiple sclerosis: The International Classification of Cognitive Disorders in MS (IC-CoDiMS).Semantic proximity Read ↗

Cognitive phenotypes in multiple sclerosis.Semantic proximity Read ↗

Molecular mechanisms associated with multiple sclerosis progression, severity and phenotypeSemantic proximity Read ↗

Contrasting genetic architectures of multiple sclerosis susceptibility and outcome phenotypes.Semantic proximity Read ↗

Progression of regional atrophy in the left hemisphere contributes to clinical and cognitive deterioration in multiple sclerosis: A 5-year study.Semantic proximity Read ↗

Structural and functional imaging features of cognitive phenotypes in pediatric multiple sclerosis.Semantic proximity Read ↗

Quantitative MRI phenotypes capture biological heterogeneity in multiple sclerosis patients.Semantic proximity Read ↗

Characterisation of MS phenotypes across the age span using a novel data set integrating 34 clinical trials (NO.MS cohort): Age is a key contributor to presentation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.