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Article

Genetic susceptibility to multiple sclerosis: Brain structure and cognitive function in the general population.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Nov 2017

Ikram Mohammad Arfan, Vernooij Meike W, Roshchupkin Gennady V, Hofman Albert, van Duijn Cornelia M, Uitterlinden André G, Niessen Wiro J, Hintzen Rogier Q, Adams Hieab Hh

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) affects brain structure and cognitive function and has a heritable component. Over a 100 common genetic risk variants have been identified, but most carriers do not develop MS. For other neurodegenerative diseases, risk variants have effects outside patient populations, but this remains uninvestigated for MS. OBJECTIVES: To study the effect of MS-associated genetic variants on...

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Identifiers

PMID: 28273768
DOI: 10.1177/1352458516682104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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