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Article

OffScan: a universal and fast CRISPR off-target sites detection tool.

BMC genomics - 5 Mar 2020

Cui Yingbo, Liao Xiangke, Peng Shaoliang, Tang Tao, Huang Chun, Yang Canqun

Abstract excerpt

BACKGROUND: The Type II clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) is a powerful genome editing technology, which is more and more popular in gene function analysis. In CRISPR/Cas, RNA guides Cas nuclease to the target site to perform DNA modification. RESULTS: The performance of CRISPR/Cas depends on well-designed single guide RNA (sgRNA). However, the...

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Identifiers

PMID: 32138651
DOI: 10.1186/s12864-019-6241-9
PMCID: PMC7057453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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