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Anti-CRISPRdb: a comprehensive online resource for anti-CRISPR proteins

14 Sept 2017

Abstract excerpt

CRISPR-Cas is a tool that is widely used for gene editing. However, unexpected off-target effects may occur as a result of long-term nuclease activity. Anti-CRISPR proteins, which are powerful molecules that inhibit the CRISPR-Cas system, may have the potential to promote better utilization of the CRISPR-Cas system in gene editing, especially for gene therapy. Additionally, more in-depth research on these...

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PMID: 29036676
DOI: 10.1093/nar/gkx835

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