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Article

The Use of the Nicotine Metabolite Ratio as a Biomarker to Personalize Smoking Cessation Treatment: Current Evidence and Future Directions.

Cancer prevention research (Philadelphia, Pa.) - 1 Mar 2020

Siegel Scott D, Lerman Caryn, Flitter Alex, Schnoll Robert A

Abstract excerpt

The nicotine metabolite ratio (NMR), a genetically informed biomarker of rate of nicotine metabolism, has been validated as a tool to select the optimal treatment for individual smokers, thereby improving treatment outcomes. This review summarizes the evidence supporting the development of the NMR as a biomarker of individual differences in nicotine metabolism, the relationship between the NMR and smoking...

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Source

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Identifiers

PMID: 32132120
DOI: 10.1158/1940-6207.CAPR-19-0259
PMCID: PMC7080293

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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