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Article

Reproducibility of the nicotine metabolite ratio in cigarette smokers.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2012

St Helen Gideon, Novalen Maria, Heitjan Daniel F, Dempsey Delia, Jacob Peyton, Aziziyeh Adel, Wing Victoria C, George Tony P, Tyndale Rachel F, Benowitz Neal L

Abstract excerpt

BACKGROUND: The nicotine metabolite ratio (NMR or 3-hydroxycotinine/cotinine) has been used to phenotype CYP2A6-mediated nicotine metabolism. Our objectives were to analyze (i) the stability of NMR in plasma, saliva, and blood in various storage conditions, (ii) the relationship between NMRs deri...

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Identifiers

PMID: 22552800
DOI: 10.1158/1055-9965.EPI-12-0236
PMCID: PMC3392523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22552800-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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