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Article

Mutation in histone deacetylase clr6 promotes the survival of S. pombe cds1 null mutant in response to hydroxyurea.

Molecular genetics and genomics : MGG - 1 May 2020

Khan Saman, Ahamad Nafees, Panigrahi Lalita, Walworth Nancy, Ahmed Shakil

Abstract excerpt

Fission yeast Cds1 is responsible for the replication checkpoint activation and helps to protect replication fork collapse in response to hydroxyurea (HU). Here, we investigated the role of histone deacetylase in response to replication fork arrest and observed that in the presence of HU, the survival of cds1Δ cells was improved when the cells were simultaneously treated with histone deacetylase inhibitors....

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Identifiers

PMID: 32124033
DOI: 10.1007/s00438-020-01655-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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