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Article

Protein phosphatase 2A (PP2A) promotes anaphase entry after DNA replication stress in budding yeast.

Molecular biology of the cell - 1 Dec 2021

Haluska Cory, Jin Fengzhi, Wang Yanchang

Abstract excerpt

DNA replication stress activates the S-phase checkpoint that arrests the cell cycle, but it is poorly understood how cells recover from this arrest. Cyclin-dependent kinase (CDK) and protein phosphatase 2A (PP2A) are key cell cycle regulators, and Cdc55 is a regulatory subunit of PP2A in budding yeast. We found that yeast cells lacking functional PP2ACdc55 showed slow growth in the presence of hydroxyurea (HU), a...

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Identifiers

PMID: 34668760
DOI: 10.1091/mbc.E21-04-0222
PMCID: PMC8694091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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