Article
Pseudouridine and N-formylmethionine associate with left ventricular mass index: Metabolome-wide association analysis of cardiac remodeling.
Journal of molecular and cellular cardiology - 1 Mar 2020
Razavi Alexander C, Bazzano Lydia A, He Jiang, Li Shengxu, Fernandez Camilo, Whelton Seamus P, Krousel-Wood Marie, Nierenberg Jovia L, Shi Mengyao, Li Changwei, Mi Xuenan, Kinchen Jason, Kelly Tanika N
Abstract excerpt
BACKGROUND: Heart failure (HF) is the fastest growing form of cardiovascular disease both nationally and globally, underlining a need to phenotype subclinical HF intermediaries to improve primary prevention. OBJECTIVES: We aimed to identify novel metabolite associations with left ventricular (LV) remodeling, one upstream HF intermediary, among a community-based cohort of individuals. METHODS: We examined 1052...
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