Article

Urolithin A induces cardioprotection and enhanced mitochondrial quality during natural aging and heart failure

2023-08-24

Abstract excerpt

Cardiovascular diseases remain the primary cause of global mortality, necessitating effective strategies to alleviate their burden. Mitochondrial dysfunction is a driving force behind aging and chronic conditions, including heart disease. Here, we investigate the potential of Urolithin A (UA), a gut microbiome-derived postbiotic that enhances mitophagy, to ameliorate both age-related decline in cardiac function an...

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Literature Corpus work: 8d146d58-00a9-503f-819b-468f297514cf
DOI: 10.1101/2023.08.22.554375

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