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Article

MicroRNA-205-5p Promotes Unstable Atherosclerotic Plaque Formation In Vivo.

Cardiovascular drugs and therapy - 1 Feb 2020

Meng Xiandong, Yin Jianjiao, Yu Xinli, Guo Yonggang

Abstract excerpt

PURPOSE: Atherosclerosis is a narrowing of the arteries caused by plaque buildup. MicroRNAs (miRNAs) have been proposed to participate in the pathogenesis of atherosclerosis. Here, we aimed to investigate miR-205-5p's role in promoting atherosclerotic progression. METHODS: Knock-in (KI) mice with human/murine miR-205-5p within the murine host gene for miR-205 (MIR205HG) were crossed with apolipoprotein E knockout...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Knockout, ApoE

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Source

Identifiers

PMID: 32034643
DOI: 10.1007/s10557-020-06935-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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