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Article

Opposing functions of miR-155-5p and Socs1 drive vascular inflammation in diabetes-accelerated atherosclerosis.

Cardiovascular diabetology - 24 Feb 2026

Kavanagh María, Herrero Del Real Isabel, Prieto Ignacio, Alvarez-Moreno Raquel, Egido Jesus, Lopez-Franco Oscar, Lázaro Iolanda, Gomez-Guerrero Carmen

Abstract excerpt

BACKGROUND: Diabetes accelerates atherosclerosis by driving persistent vascular inflammation. MicroRNA-155 (miR-155) is a post-transcriptional regulator of inflammatory genes, while suppressor of cytokine signaling 1 (Socs1) limits Janus kinase (JAK)/signal transducer and activator of transcription (STAT)-mediated cytokine responses. We explored how the imbalance between miR-155-5p and Socs1 contributes to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41736028
DOI: 10.1186/s12933-026-03121-3
PMCID: PMC13040752

Genes

STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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