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Article

Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development

23 Oct 2019

Abstract excerpt

The two-meter-long DNA is compressed into chromatin in the nucleus of every cell, which serves as a significant barrier to transcription. Therefore, for processes such as replication and transcription to occur, the highly compacted chromatin must be relaxed, and the processes required for chromatin reorganization for the aim of replication or transcription are controlled by ATP-dependent nucleosome remodelers....

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PMID: 31652801
DOI: 10.3390/ijms20215260

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