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Article

Behavioral responses of mGluR3-KO mice to the lipopolysaccharide-induced innate inflammatory reaction.

Pharmacology, biochemistry, and behavior - 1 Mar 2020

Lainiola Mira, Linden Anni-Maija, Aitta-Aho Teemu

Abstract excerpt

Acute lipopolysaccharide (LPS) administration induces innate inflammatory signalling and produces sickness reaction characterized by reduced drinking, eating and reduced locomotor exploration, as well as emotional changes indicating increased helplessness/despair. LPS administration has been used to model behavioral and emotional responses to inflammatory reactions. Our aim was to find out whether the lack of...

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Identifiers

PMID: 31952939
DOI: 10.1016/j.pbb.2020.172852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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