Article
Prenatal lipopolysaccharide exposure affects sexual dimorphism in different germlines of mice with a depressive phenotype.
Life sciences - 15 Mar 2016
Reis-Silva Thiago M, Cohn Daniel W H, Sandini Thaísa M, Udo Mariana S B, Teodorov Elizabeth, Bernardi Maria Martha
Abstract excerpt
The objective of the present study was to investigate whether prenatal lipopolysaccharide (LPS) administration modifies the expression of depressive and non-depressive-like behavior in male and female mice across two generations. The sexual dimorphism of these mice was also examined in the open-field test. Male and female mice of the parental (F0) generation were selected for depressive- or non-depressive-like...
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