Article

Metabotropic Glutamate Receptor 5 Knockout Rescues Obesity Phenotype in a Mice Model of Huntington´s Disease

2021-09-01

Abstract excerpt

Obesity represents a serious global public health problem and is characterized by a low-grade chronic inflammatory state, which can increase the risk of comorbidities, such as: atherosclerosis, diabetes and insulin resistance. In this study, we investigated the effects of the genetic deletion of the metabotropic glutamate receptor 5 (mGluR5) on the modulation of obesity features in BACHD mice, a mouse model of Hun...

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Literature Corpus work: 0b8d6d2e-0927-5b3d-b5fa-d6efc3800c07
DOI: 10.21203/rs.3.rs-842512/v1

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