Article
Channelrhodopsin-2 Oligomerization in Cell Membrane Revealed by Photo-Activated Localization Microscopy.
Angewandte Chemie (International ed. in English) - 11 Mar 2024
Bestsennaia Ekaterina, Maslov Ivan, Balandin Taras, Alekseev Alexey, Yudenko Anna, Abu Shamseye Assalla, Zabelskii Dmitrii, Baumann Arnd, Catapano Claudia, Karathanasis Christos, Gordeliy Valentin, Heilemann Mike, Gensch Thomas, Borshchevskiy Valentin
Abstract excerpt
Microbial rhodopsins are retinal membrane proteins that found a broad application in optogenetics. The oligomeric state of rhodopsins is important for their functionality and stability. Of particular interest is the oligomeric state in the cellular native membrane environment. Fluorescence microscopy provides powerful tools to determine the oligomeric state of membrane proteins directly in cells. Among these...
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