Article
Prediction and targeting of GPCR oligomer interfaces.
Progress in molecular biology and translational science - 1 Jan 2020
Barreto Carlos A V, Baptista Salete J, Preto António José, Matos-Filipe Pedro, Mourão Joana, Melo Rita, Moreira Irina
Abstract excerpt
GPCR oligomerization has emerged as a hot topic in the GPCR field in the last years. Receptors that are part of these oligomers can influence each other's function, although it is not yet entirely understood how these interactions work. The existence of such a highly complex network of interactions between GPCRs generates the possibility of alternative targets for new therapeutic approaches. However, challenges...
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