Article
Monomeric rhodopsin is sufficient for normal rhodopsin kinase (GRK1) phosphorylation and arrestin-1 binding.
The Journal of biological chemistry - 14 Jan 2011
Bayburt Timothy H, Vishnivetskiy Sergey A, McLean Mark A, Morizumi Takefumi, Huang Chih-Chin, Tesmer John J G, Ernst Oliver P, Sligar Stephen G, Gurevich Vsevolod V
Abstract excerpt
G-protein-coupled receptor (GPCR) oligomerization has been observed in a wide variety of experimental contexts, but the functional significance of this phenomenon at different stages of the life cycle of class A GPCRs remains to be elucidated. Rhodopsin (Rh), a prototypical class A GPCR of visual transduction, is also capable of forming dimers and higher order oligomers. The recent demonstration that Rh monomer...
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