Article
Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors.
Heart rhythm - 1 May 2020
Okubo Yousaku, Nakano Yukiko, Ochi Hidenori, Onohara Yuko, Tokuyama Takehito, Motoda Chikaaki, Amioka Michitaka, Hironobe Naoya, Okamura Sho, Ikeuchi Yoshihiro, Miyauchi Syunsuke, Chayama Kazuaki, Kihara Yasuki
Abstract excerpt
BACKGROUND: Atrial fibrillation (AF) has a genetic basis, and environmental factors can modify its actual pathogenesis. OBJECTIVE: The purpose of this study was to construct a combined risk assessment method including both genetic and clinical factors in the Japanese population. METHODS: We screened a cohort of 540 AF patients and 520 non-AF controls for single nucleotide polymorphisms (SNPs) previously...
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